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A recent publication from JAMA on the analysis of people who have been taking GLP-1 agonists from 2006 to 2020 shows that people who are taking GLP-1 agonists have a nine-fold higher risk of developing acute pancreatitis compared with the older drug for weight loss, bupropion, and four times more frequent intestinal obstruction and three times more frequent gastroparesis

Whether GLP1-RA improve or worsen eating disorders is an important clinical question

Chronic stress may elevate cortisol levels, making weight management more difficult

Common side effects tend to be mild and go away the longer you are on the medication

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